Uridine Active Pharmaceutical Ingredient from Trusted China Suppliers and Leading Factory
Basic Information
Uridine is a glycosylated pyrimidine-analog consisting of uracil attached to a ribose ring (ribofuranose) through a β-N₁-glycosidic bond — one of the five standard nucleosides that constitute nucleic acids.
The five standard nucleosides and their one-letter codes are:
- 🔵U — Uridine
- 🟢A — Adenosine
- 🟡T — Thymidine (more precisely written as dT)
- 🟠C — Cytidine
- 🔴G — Guanosine
Thymidine is more frequently written as 'dT', where the 'd' stands for 'deoxy'. This is because thymidine contains a 2'-deoxyribofuranose moiety, in contrast to the ribofuranose ring present in uridine. Thymidine is a component of deoxyribonucleic acid (DNA), while uridine is found in ribonucleic acid (RNA). The remaining three nucleosides (adenosine, cytidine, and guanosine) can be present in both RNA and DNA. In RNA, they are represented as A, C, and G, and in DNA, they are represented as dA, dC, and dG.
| Items | Specification |
| Description | White or almost white crystalline powder |
| Identification | The largest absorption at 262±2nm wavelength and the minimum absorption at 231±2nm A250/A260 = 0.70–0.80 | A280/A260 = 0.32–0.38 |
| Clarity and Color of Solution | Clarify |
| Loss on Drying | ≤ 0.5% |
| Rotation | +6.0° – +10.0° |
| Ignition Residue | ≤ 0.1% |
| Purity (HPLC) | ≥ 98.0% |
| Contents (Dry Basis) | 98.0% – 102.0% |
Uridine has multiple applications in the medical field. It can be used as a medicine to treat various conditions such as:
- 💊Macrocytic anemia
- 🫀Cardiovascular diseases
- 🧠Cerebrovascular diseases
- 🩺Liver diseases
Moreover, it serves as the main raw material for the production of several important drugs, including:
- ⚗️Fluorouracil (S-FC) — a well-known anti-cancer drug
- ⚗️Idoxuridine (IDUR)
- ⚗️Bromodeoxyuridine (BUDR)
- ⚗️Fluorodeoxyuridine (FUDR)
- ⚗️Deoxyribonucleoside
