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S-Adenosyl-L-methionine Disulfate Tosylate - Premium China Suppliers and Factory for Quality Supply

Basic Information

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  • Product Name S-Adenosyl-L-methionine Disulfate Tosylate (SAMe)
  • CAS Number 97540-22-2
  • EINECS Number 249-946-8
  • Molecular Formula C22H32N6O15S4
  • Molecular Weight 748.78068

Applications
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Chemical Structure

A compound combining S-adenosyl-L-methionine (SAMe) with tosylate and sulfate counterions, featuring amino, hydroxyl, and heterocyclic functional groups.

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Appearance

White to off-white crystalline powder

S-Adenosyl-L-methionine Disulfate Tosylate (1)
Main Functions
S-Adenosyl-L-methionine Disulfate Tosylate (2)
Mood Regulation & Cognitive Support
😊
Promotes Positive Mood Balance

S-Adenosyl-L-methionine Disulfate Tosylate (SAMe) plays a pivotal role in enhancing the brain's metabolism of dopamine and serotonin. These are key neurotransmitters intricately linked to emotional well-being. By optimizing their function, SAMe can effectively aid in alleviating symptoms of low mood, such as persistent sadness, lack of interest, and general emotional distress. Moreover, it provides robust support for mental clarity, enabling individuals to think more clearly and make better decisions.

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Neuroprotective Properties

SAMe has the remarkable ability to facilitate the smooth transfer of information between neurons. This neural communication is fundamental for proper cognitive function. By ensuring efficient information flow, it has the potential to improve memory retention and recall, as well as focus and concentration — beneficial for academic, professional, or daily life settings.

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Stress Resilience Enhancement: Chronic stress can have a detrimental impact on both mental and physical health. SAMe helps the body better cope with stress by regulating the hypothalamic-pituitary-adrenal (HPA) axis — the body's central stress response system. By maintaining a balanced HPA axis function, it reduces the negative effects of stress on the brain, such as anxiety and cognitive impairment, and promotes overall stress resilience.

Main Functions
S-Adenosyl-L-methionine Disulfate Tosylate (3)
Joint Health Improvement
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Pain Relief

SAMe demonstrates significant analgesic effects by modulating pain perception pathways. In conditions like osteoarthritis or inflammatory joint diseases, SAMe can reduce discomfort by interfering with the signals that transmit pain from the affected joints to the brain, allowing individuals to experience less pain and an improved quality of life.

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Functional Enhancement

SAMe actively supports joint health by promoting cartilage health and synovial fluid production. Cartilage acts as a cushion between joints, reducing friction and wear. Synovial fluid lubricates the joints, facilitating smooth movement. By enhancing these two components, SAMe improves joint mobility and flexibility, enabling individuals to perform daily activities with greater ease.

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Anti-Inflammatory Action: Inflammation is a common underlying factor in many joint conditions. SAMe has anti-inflammatory properties that help reduce joint inflammation. By inhibiting the production of pro-inflammatory cytokines and other inflammatory mediators, it can alleviate swelling, redness, and heat in the joints, further contributing to improved joint function and comfort.

Technical Data
Quality Standard Enterprise Standard  USP
Purity ≥ 98%
Solubility Soluble in water (specific solubility data may require technical datasheet reference)
Stability Light-sensitive; requires controlled storage to maintain efficacy.
Storage Guidelines
Conditions Store in a tightly sealed container under refrigeration (2–8°C).
Protection Shielded from light and moisture to prevent degradation.
Shelf Life Refer to product label/COA for expiration details; typically 24 months under proper storage.
Application References
💊 Pharmaceuticals

Used in nutraceutical formulations targeting mood disorders or joint health supplements.

🔭 Research

Valued in biochemical studies exploring neurotransmitter dynamics or osteoarthritis therapies.

Safety & Compliance
Safety Profile

Generally well-tolerated when used as directed. Consult material safety data sheets (MSDS) for handling precautions.

📋 Regulatory Status

Compliant with enterprise standards; users must verify compliance with local regulations for specific applications.

Frequently Asked Questions (FAQ)
What is S-Adenosyl-L-methionine Disulfate Tosylate (SAMe)?
S-Adenosyl-L-methionine Disulfate Tosylate (SAMe) is a stable salt form of S-adenosyl-L-methionine, combining SAMe with tosylate and sulfate counterions. It appears as a white to off-white crystalline powder and is widely used in pharmaceutical and nutraceutical applications for its mood-regulating and joint health benefits.
How does SAMe support mood and cognitive function?
SAMe enhances the brain's metabolism of key neurotransmitters, including dopamine and serotonin, which are closely linked to emotional well-being. It also facilitates efficient neural communication, supporting memory, focus, and concentration, while helping to regulate the HPA axis to improve stress resilience.
Can SAMe help with joint pain and inflammation?
Yes. SAMe has demonstrated significant analgesic and anti-inflammatory properties. It modulates pain perception pathways, promotes cartilage health and synovial fluid production, and inhibits pro-inflammatory cytokines — all of which contribute to reduced joint pain, improved mobility, and better overall joint function.
What is the purity and quality standard of this product?
This product meets Enterprise Standard and USP quality requirements, with a purity of ≥ 98%. It is soluble in water and is light-sensitive, requiring controlled storage conditions to maintain its efficacy.
What are the recommended storage conditions for SAMe Disulfate Tosylate?
The product should be stored in a tightly sealed container under refrigeration at 2–8°C, protected from light and moisture to prevent degradation. Under proper storage conditions, the typical shelf life is 24 months. Please refer to the product label or Certificate of Analysis (COA) for specific expiration details.
Is SAMe Disulfate Tosylate safe to use, and is it regulatory compliant?
SAMe Disulfate Tosylate is generally well-tolerated when used as directed. It complies with enterprise standards. However, users are advised to consult the Material Safety Data Sheet (MSDS) for handling precautions and to verify compliance with local regulations for their specific application or market.

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