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S-Adenosyl-L-methionine Disulfate Tosylate from China Suppliers and Factory - Quality Product for Your Needs

Basic Information

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  • Product Name S-Adenosyl-L-methionine Disulfate Tosylate (SAMe)
  • CAS Number 97540-22-2
  • EINECS Number 249-946-8
  • Molecular Formula C22H32N6O15S4
  • Molecular Weight 748.78068

Applications

Chemical StructureA compound combining S-adenosyl-L-methionine (SAMe) with tosylate and sulfate counterions, featuring amino, hydroxyl, and heterocyclic functional groups.

AppearanceWhite to off-white crystalline powder

S-Adenosyl-L-methionine Disulfate Tosylate (1)

Main Functions
S-Adenosyl-L-methionine Disulfate Tosylate (2)
🧠 Mood Regulation & Cognitive Support
Promotes Positive Mood Balance

S-Adenosyl-L-methionine Disulfate Tosylate (SAMe) plays a pivotal role in enhancing the brain's metabolism of dopamine and serotonin. These are key neurotransmitters intricately linked to emotional well-being. By optimizing their function, SAMe can effectively aid in alleviating symptoms of low mood, such as persistent sadness, lack of interest, and general emotional distress. Moreover, it provides robust support for mental clarity, enabling individuals to think more clearly and make better decisions.

Neuroprotective Properties

SAMe has the remarkable ability to facilitate the smooth transfer of information between neurons. By ensuring efficient information flow, it has the potential to improve various cognitive functions, including memory retention and recall, as well as focus and concentration — beneficial for academic, professional, or daily life settings.

⚡ Stress Resilience Enhancement: Chronic stress can have a detrimental impact on both mental and physical health. SAMe helps the body better cope with stress by regulating the hypothalamic-pituitary-adrenal (HPA) axis — the body's central stress response system. By maintaining a balanced HPA axis function, it reduces the negative effects of stress on the brain, such as anxiety and cognitive impairment, and promotes overall stress resilience.

Main Functions
S-Adenosyl-L-methionine Disulfate Tosylate (3)
🦴 Joint Health Improvement
Pain Relief

SAMe demonstrates significant analgesic effects by modulating pain perception pathways. In conditions like osteoarthritis or inflammatory joint diseases, SAMe can reduce discomfort by interfering with the signals that transmit pain from the affected joints to the brain, allowing individuals to experience less pain and an improved quality of life.

Functional Enhancement

SAMe actively supports joint health by promoting cartilage health and synovial fluid production. Cartilage acts as a cushion between joints, reducing friction and wear. Synovial fluid lubricates the joints, facilitating smooth movement. By enhancing these two components, SAMe improves joint mobility and flexibility, enabling easier daily activities and reducing the risk of further joint damage.

🔥 Anti-Inflammatory Action: Inflammation is a common underlying factor in many joint conditions. SAMe has anti-inflammatory properties that help reduce joint inflammation. By inhibiting the production of pro-inflammatory cytokines and other inflammatory mediators, it can alleviate swelling, redness, and heat in the joints, further contributing to improved joint function and comfort.

Technical Data
Parameter Details
Quality Standard Enterprise Standard  USP
Purity ≥ 98%
Solubility Soluble in water (specific solubility data may require technical datasheet reference)
Stability Light-sensitive; requires controlled storage to maintain efficacy.
Storage Conditions Store in a tightly sealed container under refrigeration (2–8°C).
Protection Shielded from light and moisture to prevent degradation.
Shelf Life Refer to product label/COA for expiration details; typically 24 months under proper storage.

Application References
💊
Pharmaceuticals

Used in nutraceutical formulations targeting mood disorders or joint health supplements.

🔬
Research

Valued in biochemical studies exploring neurotransmitter dynamics or osteoarthritis therapies.


Safety & Compliance
🛡️
Safety Profile

Generally well-tolerated when used as directed. Consult material safety data sheets (MSDS) for handling precautions.

Regulatory Status

Compliant with enterprise standards; users must verify compliance with local regulations for specific applications.


Frequently Asked Questions (FAQ)
Q What is S-Adenosyl-L-methionine Disulfate Tosylate (SAMe) and how does it differ from regular SAMe?
S-Adenosyl-L-methionine Disulfate Tosylate is a stabilized salt form of SAMe, combining the active SAMe molecule with tosylate and sulfate counterions. This formulation enhances the compound's stability and bioavailability compared to free-form SAMe, making it more suitable for pharmaceutical and nutraceutical applications where shelf life and consistent potency are critical.
Q What are the primary health benefits supported by SAMe Disulfate Tosylate?
SAMe Disulfate Tosylate is primarily recognized for two major areas: mood regulation and cognitive support (via dopamine and serotonin metabolism enhancement), and joint health improvement (through analgesic, anti-inflammatory, and cartilage-supportive mechanisms). It also supports stress resilience by modulating the HPA axis.
Q What purity level does this product meet, and what quality standards apply?
This product achieves a purity of ≥ 98% and complies with Enterprise Standard USP (United States Pharmacopeia) requirements. Users are advised to consult the Certificate of Analysis (COA) for batch-specific purity data and to verify compliance with applicable local regulations for their intended application.
Q How should SAMe Disulfate Tosylate be stored to maintain its efficacy?
The product should be stored in a tightly sealed container under refrigeration at 2–8°C. Because it is light-sensitive, it must be shielded from direct light and kept away from moisture to prevent degradation. Under proper storage conditions, the typical shelf life is 24 months. Always refer to the product label or COA for specific expiration details.
Q Is SAMe Disulfate Tosylate suitable for use in pharmaceutical formulations and research?
Yes. SAMe Disulfate Tosylate is widely used in nutraceutical and pharmaceutical formulations targeting mood disorders and joint health supplements. It is also a valued compound in biochemical research, particularly in studies exploring neurotransmitter dynamics and osteoarthritis therapies. Its high purity and USP-compliant quality make it appropriate for both commercial product development and scientific investigation.
Q Are there any safety concerns or regulatory considerations when using this compound?
SAMe Disulfate Tosylate is generally well-tolerated when used as directed. For safe handling, users should consult the Material Safety Data Sheet (MSDS) associated with the product. From a regulatory perspective, the product is compliant with enterprise standards; however, end users are responsible for verifying that its use meets all local regulatory requirements for their specific application or market.

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