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S-Adenosyl-L-methionine Disulfate Tosylate - China Suppliers & Factory of High-Quality SAMe Products

Basic Information

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  • Product Name S-Adenosyl-L-methionine Disulfate Tosylate (SAMe)
  • CAS Number 97540-22-2
  • EINECS Number 249-946-8
  • Molecular Formula C22H32N6O15S4
  • Molecular Weight 748.78068

Applications

Chemical Structure: A compound combining S-adenosyl-L-methionine (SAMe) with tosylate and sulfate counterions, featuring amino, hydroxyl, and heterocyclic functional groups.

Appearance: White to off-white crystalline powder

S-Adenosyl-L-methionine Disulfate Tosylate (1)

Main Functions
S-Adenosyl-L-methionine Disulfate Tosylate (2)
Mood Regulation & Cognitive Support

Promotes Positive Mood Balance: S-Adenosyl-L-methionine Disulfate Tosylate (SAMe) plays a pivotal role in enhancing the brain's metabolism of dopamine and serotonin. These are key neurotransmitters that are intricately linked to emotional well-being. By optimizing their function, SAMe can effectively aid in alleviating symptoms of low mood, such as persistent sadness, lack of interest, and general emotional distress. Moreover, it provides robust support for mental clarity, enabling individuals to think more clearly and make better decisions.

Neuroprotective Properties: SAMe has the remarkable ability to facilitate the smooth transfer of information between neurons. This neural communication is fundamental for proper cognitive function. By ensuring efficient information flow, it has the potential to improve various cognitive functions, including memory retention and recall, as well as focus and concentration.

🧠Stress Resilience Enhancement: Chronic stress can have a detrimental impact on both mental and physical health. SAMe helps the body better cope with stress by regulating the hypothalamic-pituitary-adrenal (HPA) axis, which is the body's central stress response system. By maintaining a balanced HPA axis function, it reduces the negative effects of stress on the brain, such as anxiety and cognitive impairment, and promotes overall stress resilience.

Main Functions
S-Adenosyl-L-methionine Disulfate Tosylate (3)
Joint Health Improvement

Pain Relief: SAMe demonstrates significant analgesic effects by modulating pain perception pathways. In conditions like osteoarthritis or inflammatory joint diseases, where pain is a major symptom, SAMe can reduce discomfort by interfering with the signals that transmit pain from the affected joints to the brain. This allows individuals to experience less pain and an improved quality of life.

Functional Enhancement: It actively supports joint health by promoting cartilage health and synovial fluid production. Cartilage acts as a cushion between joints, reducing friction and wear and tear. Synovial fluid lubricates the joints, facilitating smooth movement. By enhancing these two components, SAMe improves joint mobility and flexibility.

🦴Anti-Inflammatory Action: Inflammation is a common underlying factor in many joint conditions. SAMe has anti-inflammatory properties that can help reduce joint inflammation. By inhibiting the production of pro-inflammatory cytokines and other inflammatory mediators, it can alleviate swelling, redness, and heat in the joints, further contributing to improved joint function and comfort.

Technical Data
Quality Standard Enterprise Standard   USP
Purity ≥ 98%
Solubility Soluble in water (specific solubility data may require technical datasheet reference)
Stability Light-sensitive; requires controlled storage to maintain efficacy.
📦  Storage Guidelines
Conditions Store in a tightly sealed container under refrigeration (2–8°C).
Protection Shielded from light and moisture to prevent degradation.
Shelf Life Refer to product label/COA for expiration details; typically 24 months under proper storage.

Application References
💊
Pharmaceuticals

Used in nutraceutical formulations targeting mood disorders or joint health supplements.

🔬
Research

Valued in biochemical studies exploring neurotransmitter dynamics or osteoarthritis therapies.


Safety & Compliance
🛡️
Safety Profile

Generally well-tolerated when used as directed. Consult material safety data sheets (MSDS) for handling precautions.

Regulatory Status

Compliant with enterprise standards; users must verify compliance with local regulations for specific applications.


Frequently Asked Questions (FAQ)
QWhat is S-Adenosyl-L-methionine Disulfate Tosylate (SAMe) and how is it different from regular SAMe?
S-Adenosyl-L-methionine Disulfate Tosylate is a stabilized salt form of SAMe, combining the active SAMe molecule with tosylate and sulfate counterions. This formulation enhances the compound's stability and shelf life compared to free-form SAMe, making it more suitable for pharmaceutical and nutraceutical manufacturing applications.
QWhat are the primary health benefits of SAMe Disulfate Tosylate?
SAMe Disulfate Tosylate offers two major areas of benefit: mood regulation and joint health. It supports the brain's metabolism of key neurotransmitters such as dopamine and serotonin for emotional well-being and cognitive clarity, while also providing analgesic, anti-inflammatory, and cartilage-supporting effects for improved joint function and comfort.
QWhat is the recommended storage condition for SAMe Disulfate Tosylate?
SAMe Disulfate Tosylate should be stored in a tightly sealed container under refrigeration at 2–8°C. It is light-sensitive and must be protected from both light and moisture to prevent degradation. Under proper storage conditions, the typical shelf life is approximately 24 months. Always refer to the product label or Certificate of Analysis (COA) for specific expiration details.
QIs SAMe Disulfate Tosylate safe to use and what is its regulatory status?
SAMe Disulfate Tosylate is generally well-tolerated when used as directed and complies with enterprise standards including USP. Users and manufacturers should consult the Material Safety Data Sheet (MSDS) for proper handling precautions and verify compliance with local regulatory requirements for their specific application or market.
QIn what industries or research fields is SAMe Disulfate Tosylate commonly used?
SAMe Disulfate Tosylate is widely used in the pharmaceutical and nutraceutical industries, particularly in formulations targeting mood disorders, cognitive health, and joint health supplements. In the research field, it is a valued compound for biochemical studies focused on neurotransmitter dynamics, neuroprotection, and osteoarthritis therapies.
QWhat purity level does SAMe Disulfate Tosylate meet and how does this affect product quality?
SAMe Disulfate Tosylate meets a purity level of ≥ 98%, conforming to Enterprise Standard and USP specifications. This high purity ensures consistency, efficacy, and safety in both pharmaceutical formulations and research applications, minimizing the presence of impurities that could interfere with biological activity or product performance.

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