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Probiotic Powder Bacillus subtilis from China Suppliers & Factory for Enhanced Gut Health
Basic Information
Product Description
Gram-positive, Catalase-positive, with the spore form, Rod-shaped bacteria, metabolism prefer mesophilic temperature and aerobic condition. It is widely found in the environment and also the animal as well the human being bodies. The spore formed Bacillus spp are with good resistant to the environment temperature, it can be long time stored in temperature around 60℃ and even can survive 20 minutes in temperature above 120℃ when the spore form in stable condition, but the animal/human gastric and water or humidity etc can help to transfer the bacteria from spore form to active status. The Bacillus bacteria is using its vegetable cell which composed of peptidoglycan to coordinate this inactive/active metabolism.
Bacillus subtilis is studied and used for long time, even much earlier than antibiotic discovery, it was regarded as the alternative medicine in a period for bacteria treatment. From the summarized study results, the metabolism of the Bacillus subtilis is mainly as:
- ✔ Oxygen Consumption & Anaerobic Boost: Aerobic metabolism helps boost other anaerobic bacteria, especially friendly lactic acid bacteria to grow up. The further metabolism from the lactic acid bacteria can also produce more organic acid to compete and inhibit the pathogens growing up.
- ✔ Enzyme Production Ability: Bacillus spp is very able to produce multi-types enzymes, such like α-amylase, protease, lipase, cellulose etc. These can be working together with other enzymes from animal/human bodies.
- ✔ Vitamins & Anti-bodies Production: Bacillus subtilis is able to produce sufficient vitamin B as well different type antibodies can be used as antibiotics like Iturin A, Chitinase, Gramidicin, Polymycin, Nystatin etc. These are working with the natural nutrition supplements as well the natural antibiotics.
💡 Due to the strong surviving ability as well the comprehensive metabolism ability, Bacillus spp in the past tens of years are widely used in the enzyme industry, animal nutrition and health, environment control etc. It is also general approved in EFSA-QPS list as well the US-GRAS list, with CFDA-approved drugs in China and popular use in Ukraine, Italy and other regions.
Product Specification
| Items | Specification |
|---|---|
| Physical & Chemical Properties | |
| Appearance | Yellow or brown powder |
| Genetic Identification | 16s-rRNA method etc. |
| Odor | No abnormal odor |
| Water activity | <0.12 |
| Moisture, % | ≤ 10.0 |
| Microbiology | |
| Viable cell count, CFU/g | ≥ 5.0×1011 |
| Non LAB count, CFU/g | ≤ 500 |
| Coliform, CFU/g | ≤ 10 |
| Yeast & Mold, CFU/g | ≤ 50 |
| Escherichia coli /25g | Negative |
| Salmonella /25g | Negative |
| Staphylococcus aureus /25g | Negative |
| Shigella /25g | Negative |
| Heavy Metals | |
| Lead (Pb) ppm | <1.0 |
| Arsenic (As) ppm | <0.5 |
| Cadmium (Cd) ppm | <1.0 |
| Mercury (Hg) ppm | <0.1 |
Applications
- 1 Medication, HealthCare, Dietary Supplements, in forms of capsules, tablet, sachets/strips, drops etc.
- 2 Animal nutrition products & Animal feed.
- 3 Animal feed starter cultures & Aquaculture feeds.
- 4 Water treatment.
- 5 Plant protection.
- 6 Environment protection, waste degradation etc.
Package
- Inner packing: aluminum foil & PE bag
- Outer packing: foam box & carton
- Packing size: 1kg–10kg or as requested
Storage & Shelf Life
❄️
At least 24 months if stored at -18°C, in a well-sealed package away from moisture and sunlight.
Frequently Asked Questions
❓ What is Bacillus subtilis and why is it beneficial?
Bacillus subtilis is a gram-positive, spore-forming, rod-shaped bacterium that has been studied and used for decades — even before the discovery of antibiotics. It is valued for its ability to produce enzymes, vitamins, and natural antibiotics, and for supporting the growth of beneficial bacteria such as lactic acid bacteria while inhibiting harmful pathogens.
❓ What is the viable cell count of this product?
The viable cell count is guaranteed at ≥ 5.0×1011 CFU/g, ensuring a high concentration of active Bacillus cells for effective performance in all intended applications.
❓ Is this Bacillus subtilis product safe and regulatory approved?
Yes. Bacillus subtilis is included on the EFSA-QPS (Qualified Presumption of Safety) list and the US-GRAS (Generally Recognized As Safe) list. There are also CFDA-approved pharmaceutical products containing Bacillus spp in China, and it is widely used in human health products in countries such as Ukraine and Italy.
❓ What are the main applications of this product?
This product is suitable for a wide range of applications including human health supplements (capsules, tablets, sachets, drops), animal nutrition and feed, aquaculture feed starter cultures, water treatment, plant protection, and environmental protection including waste degradation.
❓ How should the product be stored and what is its shelf life?
The product should be stored at -18°C in a well-sealed package, kept away from moisture and direct sunlight. Under these conditions, the shelf life is at least 24 months from the date of manufacture.
❓ What packaging options are available?
The product is packed in an inner aluminum foil & PE bag for protection, placed inside a foam box and outer carton. Standard packing sizes range from 1kg to 10kg, and customized packing sizes are available upon request.