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High-Quality S-Adenosyl-L-methionine Disulfate Tosylate from China Suppliers and Factory for Optimal Health

Basic Information

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  • Product Name S-Adenosyl-L-methionine Disulfate Tosylate (SAMe)
  • CAS Number 97540-22-2
  • EINECS Number 249-946-8
  • Molecular Formula C22H32N6O15S4
  • Molecular Weight 748.78068

Applications
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Chemical Structure: A compound combining S-adenosyl-L-methionine (SAMe) with tosylate and sulfate counterions, featuring amino, hydroxyl, and heterocyclic functional groups.

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Appearance: White to off-white crystalline powder

S-Adenosyl-L-methionine Disulfate Tosylate (1)

Main Functions
S-Adenosyl-L-methionine Disulfate Tosylate (2)

Mood Regulation & Cognitive Support

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Promotes Positive Mood Balance: S-Adenosyl-L-methionine Disulfate Tosylate (SAMe) plays a pivotal role in enhancing the brain's metabolism of dopamine and serotonin. These are key neurotransmitters intricately linked to emotional well-being. By optimizing their function, SAMe can effectively aid in alleviating symptoms of low mood, such as persistent sadness, lack of interest, and general emotional distress, while providing robust support for mental clarity.

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Neuroprotective Properties: SAMe facilitates the smooth transfer of information between neurons — fundamental for proper cognitive function. By ensuring efficient information flow, it has the potential to improve memory retention and recall, as well as focus and concentration, benefiting academic, professional, and daily life performance.

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Stress Resilience Enhancement: Chronic stress can have a detrimental impact on both mental and physical health. SAMe helps the body better cope with stress by regulating the hypothalamic-pituitary-adrenal (HPA) axis — the body's central stress response system. By maintaining a balanced HPA axis function, it reduces the negative effects of stress on the brain, such as anxiety and cognitive impairment, and promotes overall stress resilience.


Main Functions
S-Adenosyl-L-methionine Disulfate Tosylate (3)

Joint Health Improvement

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Pain Relief: SAMe demonstrates significant analgesic effects by modulating pain perception pathways. In conditions like osteoarthritis or inflammatory joint diseases, SAMe can reduce discomfort by interfering with the signals that transmit pain from the affected joints to the brain, allowing individuals to experience less pain and an improved quality of life.

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Functional Enhancement: SAMe actively supports joint health by promoting cartilage health and synovial fluid production. Cartilage acts as a cushion between joints, reducing friction and wear and tear. Synovial fluid lubricates the joints, facilitating smooth movement. By enhancing these two components, SAMe improves joint mobility and flexibility, reducing the risk of further joint damage.

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Anti-Inflammatory Action: Inflammation is a common underlying factor in many joint conditions. SAMe has anti-inflammatory properties that help reduce joint inflammation. By inhibiting the production of pro-inflammatory cytokines and other inflammatory mediators, it can alleviate swelling, redness, and heat in the joints, further contributing to improved joint function and comfort.


Technical Data
Parameter Details
Quality Standard Enterprise Standard  |  USP
Purity ≥ 98%
Solubility Soluble in water (specific solubility data may require technical datasheet reference)
Stability Light-sensitive; requires controlled storage to maintain efficacy.
Storage Guidelines
Conditions Store in a tightly sealed container under refrigeration (2–8°C).
Protection Shielded from light and moisture to prevent degradation.
Shelf Life Refer to product label/COA for expiration details; typically 24 months under proper storage.

Application References
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Pharmaceuticals

Used in nutraceutical formulations targeting mood disorders or joint health supplements.

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Research

Valued in biochemical studies exploring neurotransmitter dynamics or osteoarthritis therapies.


Safety & Compliance
Safety Profile

Generally well-tolerated when used as directed. Consult material safety data sheets (MSDS) for handling precautions.

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Regulatory Status

Compliant with enterprise standards; users must verify compliance with local regulations for specific applications.


Frequently Asked Questions
What is S-Adenosyl-L-methionine Disulfate Tosylate (SAMe)?
S-Adenosyl-L-methionine Disulfate Tosylate is a stable salt form of SAMe, combining S-adenosyl-L-methionine with tosylate and sulfate counterions. It appears as a white to off-white crystalline powder and is widely used in nutraceutical and pharmaceutical applications for its mood-supporting and joint health benefits.
How does SAMe support mood and cognitive function?
SAMe enhances the brain's metabolism of dopamine and serotonin — key neurotransmitters linked to emotional well-being and cognitive performance. It also facilitates efficient neural communication, which supports memory, focus, and concentration, while helping regulate the HPA axis to improve stress resilience.
What are the joint health benefits of SAMe?
SAMe provides multiple joint health benefits: it modulates pain perception pathways to reduce discomfort, promotes cartilage health and synovial fluid production to improve joint mobility, and exerts anti-inflammatory effects by inhibiting pro-inflammatory cytokines, helping alleviate swelling and stiffness.
What is the recommended storage condition for SAMe Disulfate Tosylate?
SAMe Disulfate Tosylate should be stored in a tightly sealed container under refrigeration at 2–8°C, protected from light and moisture to prevent degradation. Under proper storage conditions, the typical shelf life is 24 months. Always refer to the product label or Certificate of Analysis (COA) for exact expiration details.
What purity level does this product meet?
This product meets a purity level of ≥ 98%, conforming to Enterprise Standard and USP quality standards. It is soluble in water, making it suitable for various formulation applications in pharmaceutical and research settings.
Is SAMe Disulfate Tosylate safe to use, and is it regulatory compliant?
SAMe Disulfate Tosylate is generally well-tolerated when used as directed. It is compliant with enterprise standards; however, users are advised to consult the material safety data sheet (MSDS) for handling precautions and to verify compliance with local regulations applicable to their specific use case or region.

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