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China Suppliers Factory for S-Adenosyl-L-Methionine Disulfate Tosylate – High-Quality Raw Material

Basic Information

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  • Product Name S-Adenosyl-L-methionine Disulfate Tosylate (SAMe)
  • CAS Number 97540-22-2
  • EINECS Number 249-946-8
  • Molecular Formula C22H32N6O15S4
  • Molecular Weight 748.78068

Applications

Chemical Structure: A compound combining S-adenosyl-L-methionine (SAMe) with tosylate and sulfate counterions, featuring amino, hydroxyl, and heterocyclic functional groups.

Appearance: White to off-white crystalline powder

S-Adenosyl-L-methionine Disulfate Tosylate (1)
Main Functions
S-Adenosyl-L-methionine Disulfate Tosylate (2)
Mood Regulation & Cognitive Support

Promotes Positive Mood Balance: SAMe plays a pivotal role in enhancing the brain's metabolism of dopamine and serotonin. These are key neurotransmitters intricately linked to emotional well-being. By optimizing their function, SAMe can effectively aid in alleviating symptoms of low mood, such as persistent sadness, lack of interest, and general emotional distress. Moreover, it provides robust support for mental clarity, enabling individuals to think more clearly and make better decisions.

Neuroprotective Properties: SAMe has the remarkable ability to facilitate the smooth transfer of information between neurons. By ensuring efficient information flow, it has the potential to improve memory retention and recall, as well as focus and concentration — beneficial for academic, professional, or daily life settings.

Stress Resilience Enhancement: Chronic stress can have a detrimental impact on both mental and physical health. SAMe helps the body better cope with stress by regulating the hypothalamic-pituitary-adrenal (HPA) axis — the body's central stress response system. By maintaining balanced HPA axis function, it reduces anxiety and cognitive impairment caused by stress and promotes overall stress resilience.

S-Adenosyl-L-methionine Disulfate Tosylate (3)
Joint Health Improvement

Pain Relief: SAMe demonstrates significant analgesic effects by modulating pain perception pathways. In conditions like osteoarthritis or inflammatory joint diseases, SAMe can reduce discomfort by interfering with the signals that transmit pain from affected joints to the brain, allowing individuals to experience less pain and an improved quality of life.

Functional Enhancement: SAMe actively supports joint health by promoting cartilage health and synovial fluid production. Cartilage acts as a cushion between joints, reducing friction and wear. Synovial fluid lubricates joints for smooth movement. By enhancing these components, SAMe improves joint mobility and flexibility.

Anti-Inflammatory Action: Inflammation is a common underlying factor in many joint conditions. SAMe has anti-inflammatory properties that help reduce joint inflammation. By inhibiting the production of pro-inflammatory cytokines and other inflammatory mediators, it alleviates swelling, redness, and heat in the joints, further contributing to improved joint function and comfort.

Technical Data
Parameter Details
Quality Standard Enterprise Standard  USP
Purity ≥ 98%
Solubility Soluble in water (specific solubility data may require technical datasheet reference)
Stability Light-sensitive; requires controlled storage to maintain efficacy.
📦 Storage Guidelines
Conditions Store in a tightly sealed container under refrigeration (2–8°C).
Protection Shielded from light and moisture to prevent degradation.
Shelf Life Refer to product label/COA for expiration details; typically 24 months under proper storage.
Application References
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Pharmaceuticals

Used in nutraceutical formulations targeting mood disorders or joint health supplements.

🔬
Research

Valued in biochemical studies exploring neurotransmitter dynamics or osteoarthritis therapies.

Safety & Compliance
🛡️
Safety Profile

Generally well-tolerated when used as directed. Consult material safety data sheets (MSDS) for handling precautions.

Regulatory Status

Compliant with enterprise standards; users must verify compliance with local regulations for specific applications.

Frequently Asked Questions (FAQ)
What is S-Adenosyl-L-methionine Disulfate Tosylate (SAMe)?
S-Adenosyl-L-methionine Disulfate Tosylate (SAMe) is a stable salt form of S-adenosyl-L-methionine, combining SAMe with tosylate and sulfate counterions. It appears as a white to off-white crystalline powder and features amino, hydroxyl, and heterocyclic functional groups, making it suitable for pharmaceutical and research applications.
How does SAMe support mood and cognitive function?
SAMe enhances the brain's metabolism of key neurotransmitters — dopamine and serotonin — which are directly linked to emotional well-being and mental clarity. It also facilitates efficient neuron-to-neuron information transfer, supporting memory, focus, and concentration, while helping regulate the HPA axis to reduce the negative effects of chronic stress.
Can SAMe help with joint pain and inflammation?
Yes. SAMe has demonstrated significant analgesic and anti-inflammatory properties. It modulates pain perception pathways to reduce discomfort in conditions like osteoarthritis, promotes cartilage health and synovial fluid production for better joint mobility, and inhibits pro-inflammatory cytokines to alleviate swelling, redness, and heat in affected joints.
What are the storage requirements for SAMe Disulfate Tosylate?
SAMe Disulfate Tosylate is light-sensitive and should be stored in a tightly sealed container under refrigeration at 2–8°C, shielded from light and moisture to prevent degradation. Under proper storage conditions, the shelf life is typically 24 months. Always refer to the product label or Certificate of Analysis (COA) for specific expiration details.
What is the purity level of this product and what quality standards does it meet?
This product meets a purity level of ≥ 98% and complies with Enterprise Standard and USP (United States Pharmacopeia) quality standards, ensuring consistent quality for pharmaceutical and research use.
Is SAMe Disulfate Tosylate safe to use, and is it regulatory compliant?
SAMe Disulfate Tosylate is generally well-tolerated when used as directed. It is compliant with enterprise standards; however, users are advised to consult the material safety data sheet (MSDS) for proper handling precautions and to verify compliance with local regulations applicable to their specific use case or region.

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