benzofuran-6-carboxylic acid

Its key physicochemical properties are as follows: it is soluble in polar organic solvents such as methanol, ethanol, dichloromethane and ethyl acetate, slightly soluble in water, and insoluble in non-polar solvents like petroleum ether and n-hexane. The melting point ranges from 180–184℃, the product purity is generally ≥98% (determined by HPLC), and the water content is ≤0.5%. The benzofuran skeleton in the molecular structure endows it with unique electronic effects and lipophilicity, and the carboxyl group can undergo condensation, amidation, esterification and other reactions, adapting to diverse subsequent synthetic reactions and providing support for constructing complex functional molecules.

In terms of safety and storage, this compound is slightly irritating to the skin, respiratory tract and eyes. Protective gloves, goggles and masks should be worn during operation to avoid direct contact and inhalation; if contact occurs accidentally, rinse the affected area with plenty of water immediately. It should be sealed in a light-proof container and stored in a cool (2–8℃), dry and well-ventilated place, away from strong oxidants and strong bases (to avoid carboxyl decarboxylation), and avoid high temperature and humid environments to prevent oxidation, degradation and other reactions, ensuring storage stability.